The preconditioning effect of sevoflurane on the oxygen glucose-deprived hippocampal slice: the role of tyrosine kinases and duration of ischemia.

@article{Sigaut2009ThePE,
  title={The preconditioning effect of sevoflurane on the oxygen glucose-deprived hippocampal slice: the role of tyrosine kinases and duration of ischemia.},
  author={St{\'e}phanie Sigaut and Virginie Jannier and Danielle Rouelle and Pierre Gressens and Jean Mantz and Souhayl Dahmani},
  journal={Anesthesia and analgesia},
  year={2009},
  volume={108 2},
  pages={601-8}
}
BACKGROUND The neuroprotective efficacy of anesthetics observed in experimental models remains unproven in the clinical setting. The nonreceptor tyrosine kinase focal adhesion kinase (FAK) has been suggested to be involved in the neuroprotective effect of anesthetics observed experimentally. In the present work, we investigated whether FAK and the duration of ischemia play a role in the preconditioning effect of sevoflurane on brain tissue. METHODS Rat acute hippocampal slices were subjected… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Sevoflurane preconditioning protects rat hippocampus against ischemic neuronal damage

  • B Lei, S Popp, C Capuano-Waters, JE Cottrell, IS. Kass
  • J Neurosurg Anesthesiol
  • 2006

The long-term effect of sevoflurane on neuronal cell damage and expression of apoptotic factors after cerebral ischemia and reperfusion in rats

  • M Pape, K Englelhard, +5 authors C. Werner
  • Anesth Analg
  • 2006

Similar Papers

Loading similar papers…