The prebiotic role of adenine: A critical analysis

  title={The prebiotic role of adenine: A critical analysis},
  author={Robert Shapiro},
  journal={Origins of Life and Evolution of the Biosphere},
  • R. Shapiro
  • Published 1 June 1995
  • Biology
  • Origins of Life and Evolution of the Biosphere
Adenine plays an essential role in replication in all known living systems today, and is prominent in many other aspects of biochemistry. It occurs among the products of oligomerization of HCN. These circumstances have stimulated the idea that adenine was a component in a replication system that was present at the start of life. Such replicators have included not only RNA, but also a number of simpler RNA-like alternatives which utilize a simpler backbone.Despite these encouraging indicators, a… 

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