The pre-S domain of the large viral envelope protein determines host range in avian hepatitis B viruses.

@article{Ishikawa1995ThePD,
  title={The pre-S domain of the large viral envelope protein determines host range in avian hepatitis B viruses.},
  author={Toshihisa Ishikawa and Donald E Ganem},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 14},
  pages={6259-63}
}
In addition to their well-recognized hepatotropism, all hepatitis B viruses (HBVs) display marked species specificity, growing poorly or not at all in species other than those closely related to their natural hosts. We have examined the molecular basis for this narrow host range, using duck HBV (DHBV) and heron HBV (HHBV) as a model system. HHBV virions… CONTINUE READING