The pp60c-Src inhibitor PP1 is non-competitive against ATP.

Abstract

Glutathione-S-transferase (GST)-pp60(c-Src) (GST-Src) expressed in Escherichia coli is as catalytically active as purified, activated pp60(c-Src) protein derived from human platelets. We utilized the bacterially expressed enzyme, together with information about the structures of Src family kinases in complex with their inhibitors PP1 and PP2, to modify PP1… (More)

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Cite this paper

@article{Karni2003ThePI, title={The pp60c-Src inhibitor PP1 is non-competitive against ATP.}, author={Rotem Karni and Sarit Mizrachi and Ella Reiss-Sklan and A. Z. Gazit and Oded Livnah and Alexander Levitzki}, journal={FEBS letters}, year={2003}, volume={537 1-3}, pages={47-52} }