The power and perils of animal models with urogenital anomalies: handle with care.

@article{Hutson2014ThePA,
  title={The power and perils of animal models with urogenital anomalies: handle with care.},
  author={John M Hutson and Laurence S. Baskin and Gail P Risbridger and Gerald R. Cunha},
  journal={Journal of pediatric urology},
  year={2014},
  volume={10 4},
  pages={699-705}
}
Congenital abnormalities of the urogenital tracts form a major part of clinical practice for paediatric urologists, but their knowledge of normal and abnormal development is often limited. Advances in understanding frequently come from studying experimental findings from animal models, however, most clinicians underestimate both the power and perils of extrapolating scientific knowledge from animals. In this review, the key issues that urologists need to understand in order to link animal… CONTINUE READING

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