The potential use of selective 5-HT2C agonists in treating obesity

@article{Smith2006ThePU,
  title={The potential use of selective 5-HT2C agonists in treating obesity},
  author={Brian M. Smith and William J. Thomsen and Andrew J. Grottick},
  journal={Expert Opinion on Investigational Drugs},
  year={2006},
  volume={15},
  pages={257 - 266}
}
Activation of central 5-HT2C receptors as a strategy for appetite suppression and weight control is supported by animal pharmacology and human clinical studies. Considerable evidence comes from the weight-loss effects of fenfluramine, a non-selective 5-HT2C agonist. Advances in molecular pharmacology have led to an understanding of the effects of 5-HT2C receptor activation on food intake and satiety, in addition to providing insight into the causes of cardiac valvular insufficiency and… 

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