The potential use of a dopamine neuron antibody and a striatal-derived neurotrophic factor as diagnostic markers in Parkinson's disease.

@article{Carvey1991ThePU,
  title={The potential use of a dopamine neuron antibody and a striatal-derived neurotrophic factor as diagnostic markers in Parkinson's disease.},
  author={Paul M. Carvey and Andrew McRae and Thomas F. Lint and Louise Ptak and Ervvin S Lo and Christopher G{\"o}tz and Harold L. Klawans},
  journal={Neurology},
  year={1991},
  volume={41 5 Suppl 2},
  pages={53-8; discussion 59-60}
}
The cerebral spinal fluid (CSF) of patients with Parkinson's disease (PD) contains an antibody that immunocytochemically reacts with dopamine (DA) neurons in the substantia nigra (SN). This antibody was found in 78% of the CSF samples taken from patients with clinical PD. In contrast, only 3% of the CSF samples taken from control patients or patients with neurologic symptoms other than PD possessed this antibody. The production of this antibody might contribute to disease progression but does… CONTINUE READING
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