The potential role of microRNAs in regulating gonadal sex differentiation in the chicken embryo

@article{Cutting2011ThePR,
  title={The potential role of microRNAs in regulating gonadal sex differentiation in the chicken embryo},
  author={Andrew D. Cutting and Stephanie C. Bannister and Tim J. Doran and Andrew H. Sinclair and Mark V. L. Tizard and Craig A Smith},
  journal={Chromosome Research},
  year={2011},
  volume={20},
  pages={201-213}
}
Differential gene expression regulates tissue morphogenesis. The embryonic gonad is a good example, where the developmental decision to become an ovary or testis is governed by female- or male-specific gene expression. A number of genes have now been identified that control gonadal sex differentiation. However, the potential role of microRNAs (miRNAs) in ovarian and testicular pathways is unknown. In this review, we summarise our current understanding of gonadal differentiation and the possible… CONTINUE READING