The potential of hyperpolarized (13)C MRI in assessing signaling pathways in cancer.

@article{Zhang2014ThePO,
  title={The potential of hyperpolarized (13)C MRI in assessing signaling pathways in cancer.},
  author={Huiming Zhang},
  journal={Academic radiology},
  year={2014},
  volume={21 2},
  pages={215-22}
}
Advances in genomics are enabling integration of various -omics to reveal the complexities underneath carcinogenesis. Multivariate signaling pathways are deregulated and evolve spatially and temporally depending on the tumor microenvironment. This finding shifts the focus of cancer research from "one disease-one target and drug" to "one disease-multiple pathway targets and combinational therapy" and imposes new challenges on the imaging community in terms of imaging targets, scales and… CONTINUE READING
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