The potential nephrotoxic effects of intensity modulated radiotherapy delivered to the para-aortic area of women with gynecologic malignancies: preliminary results.

@article{Varlotto2006ThePN,
  title={The potential nephrotoxic effects of intensity modulated radiotherapy delivered to the para-aortic area of women with gynecologic malignancies: preliminary results.},
  author={John Michael Varlotto and Kristina Gerszten and D E Heron and John T. Comerci and Shiva Gautam and Raj N Selvaraj and Ron J Lalonde and Justin C Chura},
  journal={American journal of clinical oncology},
  year={2006},
  volume={29 3},
  pages={281-9}
}
OBJECTIVE To assess kidney function via creatinine clearance before and after radiotherapy in gynecologic cancer patients treated to the para-aortic (PA) area via Intensity Modulated Radiotherapy (IMRT). METHODS Twenty-three patients underwent IMRT to the para-aortic area, were followed for at least 5 months, and had the necessary laboratory data to calculate creatinine clearance. Various patient-related factors and radiotherapy-treatment related factors were analyzed to determine their… CONTINUE READING