The potential impact of structural genomics on tuberculosis drug discovery.

@article{Arcus2006ThePI,
  title={The potential impact of structural genomics on tuberculosis drug discovery.},
  author={Vickery L Arcus and J. Shaun Lott and J M Johnston and Edward N Baker},
  journal={Drug discovery today},
  year={2006},
  volume={11 1-2},
  pages={28-34}
}
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB) in humans, is a devastating infectious organism that kills approximately two million people annually. The current suite of antibiotics used to treat TB faces two main difficulties: (i) the emergence of multidrug-resistant (MDR) strains of M. tuberculosis, and (ii) the persistent state of… CONTINUE READING