The potential impact of native Australian trypanosome infections on the health of koalas (Phascolarctos cinereus)

@article{McInnes2011ThePI,
  title={The potential impact of native Australian trypanosome infections on the health of koalas (Phascolarctos cinereus)},
  author={Linda M. McInnes and Amber K. Gillett and Jon Hanger and Simon A. Reid and Una M. Ryan},
  journal={Parasitology},
  year={2011},
  volume={138},
  pages={873 - 883}
}
SUMMARY Whole blood collected from koalas admitted to the Australian Zoo Wildlife Hospital (AZWH), Beerwah, QLd, Australia, during late 2006–2009 was tested using trypanosome species-specific 18S rDNA PCRs designed to amplify DNA from Trypanosoma irwini, T. gilletti and T. copemani. Clinical records for each koala sampled were reviewed and age, sex, blood packed cell volume (PCV), body condition, signs of illness, blood loss, trauma, chlamydiosis, bone marrow disease, koala AIDS and hospital… 
Increased Trypanosoma spp. richness and prevalence of haemoparasite co-infection following translocation
TLDR
The response of haemoparasites to translocation was highly site-specific, with predominant changes to the haemiparasite community in translocated woylies occurring within the first few months following translocation.
Blood Parasites in Endangered Wildlife-Trypanosomes Discovered during a Survey of Haemoprotozoa from the Tasmanian Devil
TLDR
This study provides the first insight into haemoprotozoa from the Tasmanian devil and the first identification of Trypanosoma and Babesia in this carnivorous marsupial.
Molecular characterization of native Australian trypanosomes in quokka (Setonix brachyurus) populations from Western Australia.
TLDR
The quokka, Setonix brachyurus, is a vulnerable, small marsupial endemic to Western Australia and blood samples were collected from quokkas from three different geographical locations; Two Peoples Bay, Bald Island and Rottnest Island, where two Trypanosoma copemani genotypes were identified.
Investigation of the morphological diversity of the potentially zoonotic Trypanosoma copemani in quokkas and Gilbert's potoroos
TLDR
It is shown for the first time that trypomastigotes are not the only life-cycle stages circulating within the blood stream of trypanosome infected Australian native marsupials and insights are provided into possible pathogenic mechanisms of this potentially zoonotic trypanOSome species.
Next generation sequencing reveals widespread trypanosome diversity and polyparasitism in marsupials from Western Australia
In Western Australia a number of indigenous Trypanosoma spp. infect susceptible native marsupials, such as the woylie (Bettongia penicillata), brushtail possum (Trichosurus vulpecula), and chuditch
Increased genetic diversity and prevalence of co-infection with Trypanosoma spp. in koalas (Phascolarctos cinereus) and their ticks identified using next-generation sequencing (NGS)
TLDR
A next-generation sequencing (NGS)-based assay was applied to characterise the prevalence and genetic diversity of trypanosome communities in koalas and two native species of ticks and results revealed that this method was only able to identify the genotypes with greater amount of reads within koala samples, which highlights the advantages of NGS in detecting mixed infections.
Trypanosome co-infections increase in a declining marsupial population
TLDR
The results suggest an interaction between the two parasites with the decline of their host, leading to a higher level of co-infection after the decline, and the importance of considering co- Infection when investigating the role of parasites in species declines.
Morphological polymorphism of Trypanosoma copemani and description of the genetically diverse T. vegrandis sp. nov. from the critically endangered Australian potoroid, the brush-tailed bettong (Bettongia penicillata (Gray, 1837))
TLDR
Here it is reported for the first time on the morphological diversity of trypanosomes infecting the woylie and provided the first visual evidence of a mixed infection of both T. vegrandis sp.
The marsupial trypanosome Trypanosoma copemani is not an obligate intracellular parasite, although it adversely affects cell health
TLDR
Trypanosoma copemani is unlikely to have an obligate intracellular life-cycle like T. cruzi and should be investigated in vivo in infected host tissues to better understand this host-parasite relationship.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 83 REFERENCES
Trypanosoma irwini n. sp (Sarcomastigophora: Trypanosomatidae) from the koala (Phascolarctos cinereus)
TLDR
Morphological analysis of bloodstream forms and phylogenetic analysis at the 18S rDNA and gGAPDH loci demonstrated this trypanosome species to be genetically distinct and most similar to Trypanosoma bennetti.
Novel trypanosome Trypanosoma gilletti sp. (Euglenozoa: Trypanosomatidae) and the extension of the host range of Trypanosoma copemani to include the koala (Phascolarctos cinereus)
TLDR
The finding of a second novel species, T. gilletti, is reported, as well as the extension of the host range of Trypanosoma copemani to include koalas, and Phylogenetic analysis at the 18S rDNA and gGAPDH loci demonstrated that T.gilletti was genetically distinct.
Clinical trypanosomosis due toTrypanosoma theileri in a cow in Iran
  • H. Seifi
  • Biology, Medicine
    Tropical Animal Health and Production
  • 2005
TLDR
A clinical case of bovine trypanosomosis due to T. theileri in Iran is reported, with a 6 year old native cow with loss of appetite and decreased milk yield admitted to the Veterinary Clinic, Urmia University.
Pathobiochemical mechanisms involved in the control of the disease caused by Trypanosoma congolense in African grey duiker (Sylvicapra grimmia).
TLDR
It is concluded that the grey duiker is inherently trypanotolerant, shown by its ability to control parasitaemia, suffer less severe anaemia, and to a relative degree resist pathobiochemical derangements of some serum and erythrocyte metabolites and enzymes.
A comparative evaluation of parasitological, serological and DNA amplification methods for diagnosis of natural Trypanosoma evansi infection in camels.
TLDR
The history of intermittent fever, emaciation, oedema, poor body condition significantly correlated with positive serological status in ELISA as well as trypanosome DNA detection by PCR.
EFFECT OF CONCURRENT INFECTIONS OF LERNAEOCERA BRANCHIALIS (COPEPODA) AND TRYPANOSOMA MURMANENSIS (PROTOZOA) ON ATLANTIC COD, GADUS MORHUA
TLDR
It is concluded that an infection with an adult L. branchialis does not impair the health of fish in this area of the northwestern Atlantic Ocean, but the presence of T. murmanensis concurrently can potentiate its effect.
A field study to estimate the prevalence of Trypanosoma equiperdum in Mongolian horses.
TLDR
Based on the clinical findings, the negative parasitological results and the concentration of conspicuous seroprevalences in single herds, circumstantial evidence supports the existence of infections with the causative agent of dourine.
Bovine trypanosomosis in the Bolivian Pantanal.
TLDR
It was concluded that trypanosomosis is a primary constraint for cattle production in the Bolivian Pantanal.
A trypanosome species isolated from naturally infected Haemaphysalis hystricis ticks in Kagoshima Prefecture, Japan
TLDR
An unknown trypanosome species isolated from naturally infected Haemaphysalis hystricis ticks is reported on and a phylogenetic tree constructed with the 18S rRNA gene indicates that Trypanosoma KG1 is a member of the stercorariantrypanosomes.
Heligmosomoides polygyrus and Trypanosoma congolense infections in mice: effect of immunisation by abbreviated larval infection.
TLDR
It is concluded that T. congolense may not completely block the strong acquired resistance induced by abbreviated H. polygyrus larval infection in TO mice but is capable of interfering with protective responses, especially if the trypanosome infection occurs prior to H.polygyrus challenge infection.
...
1
2
3
4
5
...