The potential impact of an HIV vaccine with limited protection on HIV incidence in Thailand: a modeling study.

@article{Nagelkerke2011ThePI,
  title={The potential impact of an HIV vaccine with limited protection on HIV incidence in Thailand: a modeling study.},
  author={Nico J. D. Nagelkerke and Jan A C Hontelez and Sake J. de Vlas},
  journal={Vaccine},
  year={2011},
  volume={29 36},
  pages={6079-85}
}
BACKGROUND The RV144 trial on the ALVAC/AIDSVAX candidate HIV vaccine, carried out in Thailand, showed short-lived protection against infection. METHODS Using a deterministic compartmental model we explored the potential impact of this vaccine on heterosexual HIV transmission in Thailand. Both one-off vaccination strategies, as well as strategies with regular boosting, either annually or every two years, were explored. Both targeting the general adult population and prioritizing sex workers… CONTINUE READING

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