The posttranslational modification of phosphoglucomutase is regulated by galactose induction and glucose repression in Saccharomyces cerevisiae.

@article{Fu1995ThePM,
  title={The posttranslational modification of phosphoglucomutase is regulated by galactose induction and glucose repression in Saccharomyces cerevisiae.},
  author={Lianwu Fu and Pam Bounelis and Nrisingha Dey and Barclay L Browne and Richard B. Marchase and David M. Bedwell},
  journal={Journal of bacteriology},
  year={1995},
  volume={177 11},
  pages={3087-94}
}
The enzyme phosphoglucomutase functions at a key point in carbohydrate metabolism. In this paper, we show that the synthesis of the major isoform of yeast phosphoglucomutase, encoded by the GAL5 (PGM2) gene, is regulated in a manner that is distinct from that previously described for other enzymes involved in galactose metabolism in the yeast Saccharomyces cerevisiae. Accumulation of this isoform increased four- to sixfold when the culture experienced either glucose depletion or heat shock… CONTINUE READING
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