The post-transplant lymphoproliferative disorder—a literature review

@article{Shroff2003ThePL,
  title={The post-transplant lymphoproliferative disorder—a literature review},
  author={Rokshana Shroff and Lesley Rees},
  journal={Pediatric Nephrology},
  year={2003},
  volume={19},
  pages={369-377}
}
The Epstein-Barr virus (EBV)-induced post-transplant lymphoproliferative disorder (PTLD) affects 1%–10% of all paediatric renal transplant recipients. This is a heterogeneous group of conditions characterised by EBV-driven proliferation of B-lymphocytes in the face of impaired T-cell immune surveillance. The risk factors predisposing to PTLD are becoming better understood, but its pathogenesis and myriad of clinical and histological features remain poorly defined. While new treatment modalities… CONTINUE READING

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