The post-transplant lymphoproliferative disorder—a literature review

  title={The post-transplant lymphoproliferative disorder—a literature review},
  author={Rokshana Shroff and Lesley Rees},
  journal={Pediatric Nephrology},
The Epstein-Barr virus (EBV)-induced post-transplant lymphoproliferative disorder (PTLD) affects 1%–10% of all paediatric renal transplant recipients. This is a heterogeneous group of conditions characterised by EBV-driven proliferation of B-lymphocytes in the face of impaired T-cell immune surveillance. The risk factors predisposing to PTLD are becoming better understood, but its pathogenesis and myriad of clinical and histological features remain poorly defined. While new treatment modalities… CONTINUE READING

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Publications referenced by this paper.
Showing 1-10 of 99 references

Recombinant vaccinia virus expressing Epstein Barr virus glycoprotein incorporated into immune-stimulating complexes

AJ Morgan, S Finerty, K Lovgren, FT Scullion, B Morein
J Gen Virol • 1988
View 8 Excerpts
Highly Influenced

A single-centre experience of post-renal transplant lymphoproliferative disorder.

Transplant international : official journal of the European Society for Organ Transplantation • 2003
View 3 Excerpts

Epstein Barr virus seronegativity is a risk factor for late onset posttransplant lymphoproliferative disorder in adult renal allograft recipients

VB Shaninian, N Muirhead, +6 authors AA House
Transplantation • 2003
View 1 Excerpt

: a report of the North American Pediatric Renal Transplant Cooperative Study ( NAPRTCS )

DP Funch, J Brady, HH Ko, NA Dreyer, AM Walker

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