The positive association between elevated blood lead levels and brain-specific autoantibodies in autistic children from low lead-polluted areas

@article{Mostafa2016ThePA,
  title={The positive association between elevated blood lead levels and brain-specific autoantibodies in autistic children from low lead-polluted areas},
  author={Gehan Mohamed Ahmed Mostafa and Geir Bj\orklund and Mauricio A Urbina and Laila Al-Ayadhi},
  journal={Metabolic Brain Disease},
  year={2016},
  volume={31},
  pages={1047-1054}
}
The underlying pathogenic mechanism in autoimmune disorders is the formation of autoantibodies. In children with autism spectrum disorder (ASD), it has been documented increased levels of brain-specific autoantibodies. Furthermore, lead (Pb) has been identified as one of the main neurotoxicants acting as environmental triggers for ASD as it induces neuroinflammation and autoimmunity. The present study is the first to explore a potential relationship between the levels of blood lead (BPb) and… CONTINUE READING
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