The population genetics of ecological specialization in evolving Escherichia coli populations

@article{Cooper2000ThePG,
  title={The population genetics of ecological specialization in evolving Escherichia coli populations},
  author={Vaughn S. Cooper and Richard E. Lenski},
  journal={Nature},
  year={2000},
  volume={407},
  pages={736-739}
}
  • Vaughn S. Cooper, Richard E. Lenski
  • Published 2000
  • Biology, Medicine
  • Nature
  • When organisms adapt genetically to one environment, they may lose fitness in other environments. Two distinct population genetic processes can produce ecological specialization—mutation accumulation and antagonistic pleiotropy. In mutation accumulation, mutations become fixed by genetic drift in genes that are not maintained by selection; adaptation to one environment and loss of adaptation to another are caused by different mutations. Antagonistic pleiotropy arises from trade-offs, such that… CONTINUE READING

    Figures and Topics from this paper.

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 387 CITATIONS, ESTIMATED 95% COVERAGE

    FILTER CITATIONS BY YEAR

    2001
    2020

    CITATION STATISTICS

    • 20 Highly Influenced Citations

    • Averaged 16 Citations per year from 2018 through 2020

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 36 REFERENCES

    Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations.