The polyubiquitin gene is essential for meiosis in fission yeast.

  title={The polyubiquitin gene is essential for meiosis in fission yeast.},
  author={Koei Okazaki and Hiroto Okayama and Osami Niwa},
  journal={Experimental cell research},
  volume={254 1},
We isolated a novel sporulation-deficient mutant of Schizosaccharomyces pombe. The mutant did not have a mitotic growth defect but aborted meiosis at the first or the second division with condensed chromosomes that failed to separate, abnormal spindle(s), and disintegrated spindle pole bodies (SPBs). During the first division, the centromeres were pulled to near the spindle poles but condensed divalent chromosomes remained at the center. The failure to proceed to anaphase was also observed… CONTINUE READING
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