The polymorphisms of LCR, E6, and E7 of HPV-58 isolates in Yunnan, Southwest China

@inproceedings{Xi2018ThePO,
  title={The polymorphisms of LCR, E6, and E7 of HPV-58 isolates in Yunnan, Southwest China},
  author={Juemin Xi and Junying Chen and Miaoling Xu and Hongying Yang and Songjiao Wen and Yue Pan and Xiaodan Wang and Chao Ye and Lijuan Qiu and Qiangming Sun},
  booktitle={Virology Journal},
  year={2018}
}
Variations in HPV LCR/E6/E7 have been shown to be associated with the viral persistence and cervical cancer development. So far, there are few reports about the polymorphisms of the HPV-58 LCR/E6/E7 sequences in Southwest China. This study aims to characterize the gene polymorphisms of the HPV-58 LCR/E6/E7 sequences in women of Southwest China, and assess the effects of variations on the immune recognition of viral E6 and E7 antigens. Twelve LCR/E6/E7 of the HPV-58 isolates were amplified and… CONTINUE READING
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