The polymorphisms of GSTM1, GSTT1, HYL1*2, and XRCC1, and aflatoxin B1-related hepatocellular carcinoma in Guangxi population, China.

@article{Long2006ThePO,
  title={The polymorphisms of GSTM1, GSTT1, HYL1*2, and XRCC1, and aflatoxin B1-related hepatocellular carcinoma in Guangxi population, China.},
  author={Xi Dai Long and Yun Ma and Yi Ping Wei and Zhou Lin Deng},
  journal={Hepatology research : the official journal of the Japan Society of Hepatology},
  year={2006},
  volume={36 1},
  pages={48-55}
}
AIM High incidence rates of hepatocellular carcinoma (HCC) in Guangxi, China, are primarily due to heavy aflatoxin B1 (AFB1) exposure via corn and groundnut consumption. This study was designed to examine the polymorphisms associated of three carcinogen-metabolizing genes (namely: GSTM1, GSTT1, and HYL1*2) and one DNA-repair gene (namely: XRCC1), and investigate their role as susceptibility markers for HCC. METHODS We conducted a case-control study including 257 cases of cancer and 649… CONTINUE READING

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