The polymorphism of transforming growth factor-beta1 gene in Japanese patients with systemic sclerosis.

Abstract

BACKGROUND Transforming growth factor (TGF)-beta has been shown to be a potent stimulator of collagen production by fibroblasts, and could play a role in the pathogenesis of systemic sclerosis (SSc). OBJECTIVE To study the possible involvement of TGF-beta1 gene polymorphism in Japanese patients with SSc. METHODS Fifty-nine patients with SSc and 110… (More)

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Cite this paper

@article{Ohtsuka2002ThePO, title={The polymorphism of transforming growth factor-beta1 gene in Japanese patients with systemic sclerosis.}, author={Tsutomu Ohtsuka and Akio Yamakage and Soji Yamazaki}, journal={The British journal of dermatology}, year={2002}, volume={147 3}, pages={458-63} }