The polyhydroxyalkanoate metabolism controls carbon and energy spillage in Pseudomonas putida.

@article{Escapa2012ThePM,
  title={The polyhydroxyalkanoate metabolism controls carbon and energy spillage in Pseudomonas putida.},
  author={Isabel F. Escapa and J{\'e}ssica Leite Garcia and Bruno B{\"u}hler and Lars Mathias Blank and Mar{\'i}a Axiliadora Prieto},
  journal={Environmental microbiology},
  year={2012},
  volume={14 4},
  pages={1049-63}
}
The synthesis and degradation of polyhydroxyalkanoates (PHAs), the storage polymer of many bacteria, is linked to the operation of central carbon metabolism. To rationalize the impact of PHA accumulation on central carbon metabolism of the prototype bacterium Pseudomonas putida, we have revisited PHA production in quantitative physiology experiments in the wild-type strain vs. a PHA negative mutant growing under low nitrogen conditions. When octanoic acid was used as PHA precursor and as carbon… CONTINUE READING

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