The polyglutamine motif is highly conserved at the Clock locus in various organisms and is not polymorphic in humans

@article{Saleem2001ThePM,
  title={The polyglutamine motif is highly conserved at the Clock locus in various organisms and is not polymorphic in humans},
  author={Quasar Saleem and Anuranjan Anand and Sanjeev R. Jain and Samir K. Brahmachari},
  journal={Human Genetics},
  year={2001},
  volume={109},
  pages={136-142}
}
Circadian rhythms play a central role in diverse physiological phenomena and the recent years have witnessed the identification of a number of genes responsible for the maintenance of these rhythms. One of these is the Clock gene, which was first identified in mouse and subsequently in a large number of organisms, including humans. The human Clock gene has been proposed as a possible candidate for disorders affected by alterations of circadian rhythm, including bipolar disorder and… CONTINUE READING
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