The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos.

@article{Satijn2001ThePG,
  title={The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos.},
  author={David P. E. Satijn and Karien M. Hamer and Jan L den Blaauwen and Arie P. Otte},
  journal={Molecular and cellular biology},
  year={2001},
  volume={21 4},
  pages={1360-9}
}
Polycomb group (PcG) proteins form multimeric protein complexes which are involved in the heritable stable repression of genes. Previously, we identified two distinct human PcG protein complexes. The EED-EZH protein complex contains the EED and EZH2 PcG proteins, and the HPC-HPH PcG complex contains the HPC, HPH, BMI1, and RING1 PcG proteins. Here we show that YY1, a homolog of the Drosophila PcG protein pleiohomeotic (Pho), interacts specificially with the human PcG protein EED but not with… CONTINUE READING

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