The podocyte protein nephrin is required for cardiac vessel formation.

@article{Wagner2011ThePP,
  title={The podocyte protein nephrin is required for cardiac vessel formation.},
  author={Nicole Wagner and H. Boyd Morrison and Sophie Pagnotta and Jean-François Michiels and Yannick Schwab and K. Tryggvason and Andreas Schedl and Kay-Dietrich Wagner},
  journal={Human molecular genetics},
  year={2011},
  volume={20 11},
  pages={2182-94}
}
Nephrin (NPHS1) has been described as an important structural protein of kidney podocytes. Mutations in this gene lead to the Finnish-type congenital nephrotic syndrome. More recently, a role of nephrin as a signalling molecule in kidney podocytes has been identified. Here, we show that nephrin not only has a function in kidney podocytes, but is also required for cardiovascular development. Nephrin is expressed in the epicardium and coronary vessels during human and mouse embryonic development… CONTINUE READING

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