The pleiotropic effects of Kaposi's sarcoma herpesvirus.

  title={The pleiotropic effects of Kaposi's sarcoma herpesvirus.},
  author={Thomas F Schulz},
  journal={The Journal of pathology},
  volume={208 2},
Kaposi's sarcoma herpesvirus (KSHV), or human herpesvirus 8 (HHV8), is an essential factor in the pathogenesis of Kaposi's sarcoma (KS), multicentric Castleman's disease (MCD), and primary effusion lymphoma (PEL). Case reports suggest an occasional involvement in bone marrow hypoplasia and haemophagocytic syndrome, but other disease associations are unconfirmed or controversial. KSHV-associated disease is of particular importance in immunosuppressed individuals, in particular in patients with… CONTINUE READING
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