The plastid DNA of the malaria parasite Plasmodium falciparum is replicated by two mechanisms.

@article{Williamson2002ThePD,
  title={The plastid DNA of the malaria parasite Plasmodium falciparum is replicated by two mechanisms.},
  author={Donald H. Williamson and Peter Rainer Preiser and Peter W Moore and Shirley McCready and M Strath and Robert J. M. Wilson},
  journal={Molecular microbiology},
  year={2002},
  volume={45 2},
  pages={533-42}
}
In common with other apicomplexan parasites, Plasmodium falciparum, a causative organism of human malaria, harbours a residual plastid derived from an ancient secondary endosymbiotic acquisition of an alga. The function of the 35 kb plastid genome is unknown, but its evolutionary origin and genetic content make it a likely target for chemotherapy. Pulsed field gel electrophoresis and ionizing radiation have shown that essentially all the plastid DNA comprises covalently closed circular monomers… CONTINUE READING

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