The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disorders

@article{Faber2009ThePZ,
  title={The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disorders},
  author={Scott Faber and Gregory M. Zinn and John C. Kern and H. M. Skip Kingston},
  journal={Biomarkers},
  year={2009},
  volume={14},
  pages={171 - 180}
}
The frequency of zinc deficiency, copper toxicity and low zinc/copper in children with autism spectrum disorders (ASDs) may indicate decrement in metallothionein system functioning. A retrospective review of plasma zinc, serum copper and zinc/copper was performed on data from 230 children with autistic disorder, pervasive developmental disorder-NOS and Asperger’s syndrome. The entire cohort’s mean zinc level was 77.2 μg dl−1, mean copper level was 131.5 μg dl−1, and mean Zn/Cu was 0.608, which… Expand
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