The plant adherin AtSCC2 is required for embryogenesis and sister-chromatid cohesion during meiosis in Arabidopsis.

@article{Sebastin2009ThePA,
  title={The plant adherin AtSCC2 is required for embryogenesis and sister-chromatid cohesion during meiosis in Arabidopsis.},
  author={Jos{\'e} Miguel Sebasti{\'a}n and Maruthachalam Ravi and S{\'e}bastien E Andreuzza and Aneesh P Panoli and Mohan Prem Anand Marimuthu and Imran Siddiqi},
  journal={The Plant journal : for cell and molecular biology},
  year={2009},
  volume={59 1},
  pages={1-13}
}
Adherin plays an important role in loading the cohesin complex onto chromosomes, and is essential for the establishment of sister-chromatid cohesion. We have identified and analyzed the Arabidopsis adherin homolog AtSCC2. Interestingly, the sequence analysis of AtSCC2 and of other putative plant adherin homologs revealed the presence of a PHD finger, which is not found in their fungal and animal counterparts. AtSCC2 is identical to EMB2773, and mutants show early embryo lethality and formation… CONTINUE READING
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ChromatidsAnatomic structure is physical part ofChromosomes
Adherin plays an important role in loading the cohesin complex onto chromosomes , and is essential for the establishment of sister - chromatid cohesion .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
Adherin plays an important role in loading the cohesin complex onto chromosomes , and is essential for the establishment of sister - chromatid cohesion .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
Adherin plays an important role in loading the cohesin complex onto chromosomes , and is essential for the establishment of sister - chromatid cohesion .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
A role for AtSCC2 in sister - chromatid cohesion was established by using conditional RNAi and examining meiotic chromosome organization .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
Adherin plays an important role in loading the cohesin complex onto chromosomes , and is essential for the establishment of sister - chromatid cohesion .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
The mutant phenotype , which included defects in chromosome organization and cohesion in prophase I , is distinct from that of the Arabidopsis cohesin mutant Atrec8 , which retains centromere cohesion up to anaphase I. Immunostaining experiments revealed the aberrant distribution of the cohesin subunit AtSCC3 on chromosomes , and defects in chromosomal axis formation , in the meiocytes of AtSCC2-RNAi lines .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
The mutant phenotype , which included defects in chromosome organization and cohesion in prophase I , is distinct from that of the Arabidopsis cohesin mutant Atrec8 , which retains centromere cohesion up to anaphase I. Immunostaining experiments revealed the aberrant distribution of the cohesin subunit AtSCC3 on chromosomes , and defects in chromosomal axis formation , in the meiocytes of AtSCC2-RNAi lines .
The mutant phenotype , which included defects in chromosome organization and cohesion in prophase I , is distinct from that of the Arabidopsis cohesin mutant Atrec8 , which retains centromere cohesion up to anaphase I. Immunostaining experiments revealed the aberrant distribution of the cohesin subunit AtSCC3 on chromosomes , and defects in chromosomal axis formation , in the meiocytes of AtSCC2-RNAi lines .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
The mutant phenotype , which included defects in chromosome organization and cohesion in prophase I , is distinct from that of the Arabidopsis cohesin mutant Atrec8 , which retains centromere cohesion up to anaphase I. Immunostaining experiments revealed the aberrant distribution of the cohesin subunit AtSCC3 on chromosomes , and defects in chromosomal axis formation , in the meiocytes of AtSCC2-RNAi lines .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
Chromosome StructuresAnatomic structure is physical part ofChromosomes
The mutant phenotype , which included defects in chromosome organization and cohesion in prophase I , is distinct from that of the Arabidopsis cohesin mutant Atrec8 , which retains centromere cohesion up to anaphase I. Immunostaining experiments revealed the aberrant distribution of the cohesin subunit AtSCC3 on chromosomes , and defects in chromosomal axis formation , in the meiocytes of AtSCC2-RNAi lines .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
AtSCC2-RNAi lines showed sterility , arising from the following defects in meiotic chromosome organization : failure of homologous pairing , loss of sister - chromatid cohesion , mixed segregation of chromosomes and chromosome fragmentation .
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