The place of genetics in ageing research

  title={The place of genetics in ageing research},
  author={Nir Barzilai and Leonard P Guarente and Thomas B. L. Kirkwood and Linda Partridge and Thomas A. Rando and Pieternella E Slagboom},
  journal={Nature Reviews Genetics},
Rapidly increasing numbers of older people present many countries with growing social and economic challenges. Yet despite the far-reaching implications of ageing, its biological basis remains a topic of much debate. Recent advances in genomics have spurred research on ageing and lifespan in human populations, adding to extensive genetic studies being carried out in model organisms. But how far is ageing controlled by our genes? In this Viewpoint, six experts present their opinions and comment… 

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The evolutionary theory of ageing explains why ageing occurs and helps to clarify how the genome shapes the ageing process, thereby aiding the study of the genetic factors that influence longevity and age-associated diseases.

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  • Biology
    Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2011
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The biology of aging: 1985–2010 and beyond

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  • Medicine, Biology
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2011
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