The pivotal role of microRNA-155 in the control of cancer.

  title={The pivotal role of microRNA-155 in the control of cancer.},
  author={Zhaolin Chen and Taotao Ma and Chen Huang and Tingting Hu and Jun Li},
  journal={Journal of cellular physiology},
  volume={229 5},
microRNAs (miRNAs) are emerging as important gene expression regulators linked to various biological processes at a posttranscriptional level. miRNAs have been known to play important roles in cell proliferation, cell differentiation, and apoptosis. Recently, accumulate studies indicate that up-regulation of miR-155 has been described in several types of human tumors. miR-155 has been considered to act as an oncogene or a tumor suppressor, depending on tumor system. Silencing oncomiRs or gene… CONTINUE READING


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