The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein

@article{Bodner1988ThePT,
  title={The pituitary-specific transcription factor GHF-1 is a homeobox-containing protein},
  author={Mordechai Bodner and Jos{\'e}-Luis Castriilo and Lars E. Theill and Thomas E. Deerinck and Michael Karin},
  journal={Cell},
  year={1988},
  volume={55},
  pages={505-518}
}
Growth hormone factor 1 (GHF-1) is a pituitary-specific transcription factor that plays a critical role in cell type-specific expression of the growth hormone (GH) gene. Here, we describe the isolation of bovine and rat GHF-1 cDNA clones. These cDNAs encode proteins whose molecular mass, 33K, is identical to purified GHF-1 and whose sequence agrees with a partial GHF-1 peptide sequence. The predicted GHF-1 sequence contains a region, near its C-terminus, that exhibits considerable similarity to… CONTINUE READING

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