The pituitary-adrenal response to novel stimulation and ether stress in young adult and aged rats

@article{Brett1983ThePR,
  title={The pituitary-adrenal response to novel stimulation and ether stress in young adult and aged rats},
  author={Linda Phillips Brett and Gary S. Chong and Sallyeana Coyle and Seymour D. Levine},
  journal={Neurobiology of Aging},
  year={1983},
  volume={4},
  pages={133-138}
}
Pituitary-adrenal responsiveness to stress induced by either psychological (novelty) or physiological (ether) stimuli was examined in young (3 to 6 months) and old (24 to 27 months) male and female rats. In Experiment 1, subjects were placed in a novel environment for 3 min. Blood samples were collected at 0, 15, 30, 45, and 60 min. In Experiment 2, a blood sample was collected from experimental subjects immediately following 15 min in a novel environment; a basal sample was collected from… CONTINUE READING
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