The physiology of the lymphatic system.

@article{Swartz2001ThePO,
  title={The physiology of the lymphatic system.},
  author={Melody A Swartz},
  journal={Advanced drug delivery reviews},
  year={2001},
  volume={50 1-2},
  pages={3-20}
}
This paper presents an overview of the anatomy, physiology, and biology of the lymphatic system specifically relevant to lymphatic drug delivery. We will briefly review the classic fluid and solute transport literature, and also examine the current research in lymphatic endothelial cell biology and tumor metastasis in the lymphatics because of the increasing potential for targeted delivery of immunomodulators, chemotherapeutics, and genetic material to specific lymph nodes (Refs. [1-7]). 
Highly Influential
This paper has highly influenced 12 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 165 extracted citations

A Model for Interstitial Drainage Through a Sliding Lymphatic Valve.

Bulletin of mathematical biology • 2015
View 9 Excerpts
Highly Influenced

Nano-chemotherapeutics: maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers.

Journal of controlled release : official journal of the Controlled Release Society • 2014
View 5 Excerpts
Highly Influenced

Mechanisms of subcutaneous absorption of rituximab in rats.

Drug metabolism and disposition: the biological fate of chemicals • 2013
View 5 Excerpts
Highly Influenced

A PBPK workflow for first-in-human dose selection of a subcutaneously administered pegylated peptide

Journal of Pharmacokinetics and Pharmacodynamics • 2015
View 3 Excerpts
Highly Influenced

Lymphatic transport and catabolism of therapeutic proteins after subcutaneous administration to rats and dogs.

Drug metabolism and disposition: the biological fate of chemicals • 2012
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…