The physiology of membrane transport and endomembrane-based signalling.

@article{Sallese2006ThePO,
  title={The physiology of membrane transport and endomembrane-based signalling.},
  author={Michele Sallese and Teodoro Pulvirenti and Alberto Luini},
  journal={The EMBO journal},
  year={2006},
  volume={25 12},
  pages={
          2663-73
        }
}
Some of the important open questions concerning the physiology of the secretory pathway relate to its homeostasis. Secretion involves a number of separate compartments for which their transport activities should be precisely cross-coordinated to avoid gross imbalances in the trafficking system. Moreover, the membrane fluxes across these compartments should be able to adapt to environmental 'requests' and to respond to extracellular signals. How is this regulation effected? Here, we consider… CONTINUE READING
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