The physiology and habitat of the last universal common ancestor

@article{Weiss2016ThePA,
  title={The physiology and habitat of the last universal common ancestor},
  author={M. C. Weiss and Filipa L. Sousa and Natalia Mrnjavac and Sinje Neukirchen and M. Roettger and S. Nelson-Sathi and W. Martin},
  journal={Nature Microbiology},
  year={2016},
  volume={1}
}
The concept of a last universal common ancestor of all cells (LUCA, or the progenote) is central to the study of early evolution and life's origin, yet information about how and where LUCA lived is lacking. [...] Key Method We investigated all clusters and phylogenetic trees for 6.1 million protein coding genes from sequenced prokaryotic genomes in order to reconstruct the microbial ecology of LUCA. Among 286,514 protein clusters, we identified 355 protein families (∼0.1%) that trace to LUCA by phylogenetic…Expand
The metabolic network of the last bacterial common ancestor
TLDR
Analysis of thousands of individual gene trees indicate that LBCA was rod-shaped and the first lineage to diverge from the ancestral bacterial stem was most similar to modern Clostridia, followed by other autotrophs that harbor the acetyl-CoA pathway. Expand
Was LUCA a Hyperthermophilic Prokaryote? The Impact-Bottleneck Hypothesis Revisited
In the Origin of Species, Darwin wrote “The affinities of all the beings of the same class have sometimes been represented by a great tree. I believe this simile largely speaks the truth.” ModernExpand
Physiology, phylogeny, and the energetic roots of life
TLDR
If the authors want a fuller picture of microbial evolution, they will have to incorporate aspects of physiology, phylogeny, and the geological record, and non-fermentative substrate level phosphorylations as they occur in some acetogens and methanogens now look like good candidate reactions for that starting point, helping to put chemical roots on life's tree. Expand
A New Analysis of Archaea–Bacteria Domain Separation: Variable Phylogenetic Distance and the Tempo of Early Evolution
TLDR
Results provide a new view of protein family evolution and temper claims about the phenotype and habitat of the LUCA. Expand
Phenotypic reconstruction of the last universal common ancestor reveals a complex cell
TLDR
The results depict LUCA as a far more complex cell than has previously been proposed, challenging the evolutionary model of increased complexity through time in prokaryotes and suggesting that early life very rapidly evolved considerable cellular complexity. Expand
The First Universal Common Ancestor ( FUCA ) as the earliest ancestor of LUCA ’ s ( Last UCA ) lineage
The existence of a common ancestor to all living organisms in Earth is a necessary corollary of Darwin idea of common ancestry. The Last Universal Common Ancestor (LUCA) has been normally consideredExpand
The First Universal Common Ancestor (FUCA) as the Earliest Ancestor of LUCA’s (Last UCA) Lineage
TLDR
The emergence of this process shared by all biological systems as a point of interest is proposed and the existence of this pre-cellular entity, named FUCA, is proposed, as the first universal common ancestor. Expand
The Evolution of Reverse Gyrase Suggests a Nonhyperthermophilic Last Universal Common Ancestor
TLDR
An exhaustive search for Reverse gyrase proteins is carried out, suggesting a nonhyperthermophilic LUCA and bacterial ancestor, with hyperthernophily emerging early in the evolution of the archaeal and bacterial domains. Expand
The Common Ancestor of All Modern Life
TLDR
It is suggested that the universal ancestor was a thermophile or hyperthermophile that thrived at a very high temperature and surrounded by a cell membrane similar to those found in modern bacteria and eukaryotes. Expand
The LUCA and its complex virome
The last universal cellular ancestor (LUCA) is the most recent population of organisms from which all cellular life on Earth descends. The reconstruction of the genome and phenotype of the LUCA is aExpand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 81 REFERENCES
A minimal estimate for the gene content of the last universal common ancestor--exobiology from a terrestrial perspective.
TLDR
A fairly complex genome similar to those of free-living prokaryotes, with a variety of functional capabilities including metabolic transformation, information processing, membrane/transport proteins and complex regulation, shared between the three domains of life, emerges as the most likely progenitor of life on Earth, with profound repercussions for planetary exploration and exobiology. Expand
The two-domain tree of life is linked to a new root for the Archaea
TLDR
The results robustly indicate a sister relationship of eukaryotes with the TACK superphylum that is strongly associated with a distinct root of the Archaea that lies within the Euryarchaeota, challenging the traditional topology of the archaeal tree. Expand
On the Origin of Heterotrophy.
TLDR
It is proposed that cell mass roughly similar to the composition of Escherichia coli was the substrate for the first chemoorganoheterotrophs, and participation of chemiosmotic coupling and flavin-based electron bifurcation in clostridial amino acid and purine fermentations is consistent with an autotrophic origin of both metabolism and heterotrophy. Expand
Origins of major archaeal clades correspond to gene acquisitions from bacteria
TLDR
To investigate the origin of higher taxa in archaea, gene distributions and gene phylogenies for the 267,568 protein-coding genes of 134 sequenced archaeal genomes are determined in the context of their homologues from 1,847 reference bacterial genomes. Expand
Comparative genomics, minimal gene-sets and the last universal common ancestor
  • E. Koonin
  • Biology, Medicine
  • Nature Reviews Microbiology
  • 2003
TLDR
The present estimate suggests a simple last universal common ancestor with only 500–600 genes, based on the principle of evolutionary parsimony, is suggested. Expand
The stepwise evolution of early life driven by energy conservation.
TLDR
It is proposed that energy conservation played the predominant role in the later evolution of anaerobic metabolisms which explains the origin and evolution of extant methanogenic pathways. Expand
Evolution of the Structure of Ferredoxin Based on Living Relics of Primitive Amino Acid Sequences
The structure of present-day ferredoxin, with its simple, inorganic active site and its functions basic to photon-energy utilization, suggests the incorporation of its prototype into metabolism veryExpand
Phylogenomic reconstruction of archaeal fatty acid metabolism.
TLDR
The presence in archaea of the genes for energy-transducing membrane enzyme complexes was found to correlate with the presence of the proposed system of fatty acid biosynthesis, and it is speculated that these membrane complexes functionally depend on fatty acid chains. Expand
The universal ancestor.
  • C. Woese
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998
TLDR
The universal phylogenetic tree is not an organismal tree at its base but gradually becomes one as its peripheral branchings emerge as the universal ancestor of all extant life is presented. Expand
On the origin of biochemistry at an alkaline hydrothermal vent
  • W. Martin, M. Russell
  • Biology, Medicine
  • Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2006
TLDR
Thermodynamic considerations related to formyl pterin synthesis suggest that the ability to harness a naturally pre-existing proton gradient at the vent–ocean interface via an ATPase is older than the able to generate a protongradient with chemistry that is specified by genes. Expand
...
1
2
3
4
5
...