The physiology and habitat of the last universal common ancestor

@article{Weiss2016ThePA,
  title={The physiology and habitat of the last universal common ancestor},
  author={Madeline C Weiss and Filipa L. Sousa and Natalia Mrnjavac and Sinje Neukirchen and Mayo Roettger and Shijulal Nelson-Sathi and William F. Martin},
  journal={Nature Microbiology},
  year={2016},
  volume={1}
}
The concept of a last universal common ancestor of all cells (LUCA, or the progenote) is central to the study of early evolution and life's origin, yet information about how and where LUCA lived is lacking. [] Key Method We investigated all clusters and phylogenetic trees for 6.1 million protein coding genes from sequenced prokaryotic genomes in order to reconstruct the microbial ecology of LUCA. Among 286,514 protein clusters, we identified 355 protein families (∼0.1%) that trace to LUCA by phylogenetic…
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Results provide a new view of protein family evolution and temper claims about the phenotype and habitat of the LUCA.
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TLDR
The results depict LUCA as a far more complex cell than has previously been proposed, challenging the evolutionary model of increased complexity through time in prokaryotes and suggesting that early life very rapidly evolved considerable cellular complexity.
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TLDR
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The Evolution of Reverse Gyrase Suggests a Nonhyperthermophilic Last Universal Common Ancestor
TLDR
An exhaustive search for Reverse gyrase proteins is carried out, suggesting a nonhyperthermophilic LUCA and bacterial ancestor, with hyperthernophily emerging early in the evolution of the archaeal and bacterial domains.
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The Common Ancestor of All Modern Life
TLDR
It is suggested that the universal ancestor was a thermophile or hyperthermophile that thrived at a very high temperature and surrounded by a cell membrane similar to those found in modern bacteria and eukaryotes.
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