The physiological disposition of p-octopamine in man
@article{Hengstmann2004ThePD, title={The physiological disposition of p-octopamine in man}, author={J. Hengstmann and W. Konen and C. Konen and M. Eichelbaum and H. Dengler}, journal={Naunyn-Schmiedeberg's Archives of Pharmacology}, year={2004}, volume={283}, pages={93-106} }
SummaryAfter oral administration of 3H-p-octopamine (8 mg≙300 μCi) more 3H-activity (93% of the dose) is excreted in the urine within 24 h than after intravenous infusion (2 mg≙300 μCi) over 2.5 h (82% of the dose). This proves that p-octopamine is absorbed quantitatively in man. The absorption proceeds rapidly, peak plasma levels are reached between 30 and 60 min.The only metabolic pathways for p-octopamine are deamination and conjugation. The predominant step is oxidative deamination by… Expand
12 Citations
Bioavailability of m-octopamine in man related to its metabolism
- Chemistry, Medicine
- European Journal of Clinical Pharmacology
- 2004
- 11
The physiological disposition of etilefrine in man
- Chemistry, Medicine
- European Journal of Clinical Pharmacology
- 2004
- 17
Physiological functions and pharmacological and toxicological effects of p-octopamine
- Biology, Medicine
- Drug and chemical toxicology
- 2015
- 15
- Highly Influenced
Analysis of octopamine in human doping control samples.
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 2012
- 11
Cytochrome P450 2D6 and 3A4 enzyme inhibition by amine stimulants in dietary supplements.
- Chemistry, Medicine
- Drug testing and analysis
- 2016
- 6
Separation of octopamine racemate on (R,S)-2-amino-1-phenylethanol imprinted polymer--Experimental and computational studies.
- Chemistry, Medicine
- Talanta
- 2016
- 19
Supplementation with a low-dose of octopamine does not influence endurance cycling performance in recreationally active men.
- Psychology, Medicine
- Journal of science and medicine in sport
- 2017
- 1
- PDF
The performance and physiological effects of caffeine and octopamine supplementation during endurance cycle exercise
- Psychology
- 2017
- Highly Influenced
- PDF
Simplifying and expanding analytical capabilities for various classes of doping agents by means of direct urine injection high performance liquid chromatography high resolution/high accuracy mass spectrometry.
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 2016
- 30
References
SHOWING 1-10 OF 17 REFERENCES
Bioavailability of m-octopamine in man related to its metabolism
- Chemistry, Medicine
- European Journal of Clinical Pharmacology
- 2004
- 11
Pharmacological action of octopamine with special reference to biochemical conversion to noradrenaline.
- Biology, Medicine
- Japanese journal of pharmacology
- 1968
- 12
SUBCELLULAR DISTRIBUTION OF SOME SYMPATHOMIMETIC AMINES AND THEIR BETA-HYDROXYLATED DERIVATIVES IN THE RAT HEART.
- Chemistry, Medicine
- The Journal of pharmacology and experimental therapeutics
- 1965
- 102
Identification of Octopamine as l-p-Hydroxyphenylethanolamine
- Chemistry, Medicine
- Nature
- 1952
- 62
- Highly Influential
Supersensitivity and subsensitivity to sympathomimetic amines.
- Biology, Medicine
- Pharmacological reviews
- 1963
- 412
THE STORAGE OF NOREPINEPHRINE AND SOME OF ITS DERIVATIVES IN BRAIN SYNAPTOSOMES.
- Chemistry, Medicine
- Life sciences
- 1965
- 34
A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter
- Chemistry
- 1960
- 6,516
PURIFICATION OF NOREPINEPHRINE STORAGE GRANULES FROM RAT HEART.
- Chemistry, Medicine
- Life sciences
- 1964
- 23