The physiological and pathophysiological roles of the GH/IGF-axis in the kidney: lessons from experimental rodent models.

@article{CingelRisti2004ThePA,
  title={The physiological and pathophysiological roles of the GH/IGF-axis in the kidney: lessons from experimental rodent models.},
  author={Vesna Cingel-Risti{\'c} and Allan Flyvbjerg and Stenvert L. S. Drop},
  journal={Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society},
  year={2004},
  volume={14 6},
  pages={418-30}
}
The growth hormone (GH)/insulin-like growth factor (IGF) system plays an important role in renal development, growth, function and pathophysiology. IGF-I has been associated with renal/glomerular hypertrophy and compensatory renal growth. Potential effects on glomerular size are of interest, since an increase in glomerular size may be permissive for the development of glomerulosclerosis. In an effort to abolish the decline of renal function and possibly to restore the renal structure, different… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…