The Effects of Acute and Chronic Diphenhydramine and Cetirizine Use on Learning and Memory in Rats
Hacettepe Universitesi Bilimsel Arastirma Projeleri Koordinasyon Birimi, Proje Numarasi: THD-2017-16553
Delineating the Transcriptional Mechanisms in Immunity behind Allergy and Asthma: Milestones and Challenges Ahead
- Biology, Medicine
The transcriptional processes that lead to the emergence of the immunological actors of allergy and asthma, i.e. Th2, type 2 Innate Lymphoid Cells (ILC2), mast, IgE plasma and regulatory T-cells (Treg), as well as to the advent of imbalances towards Th2 responses in pathological cases are described.
Histoire de l’anaphylaxie et de l’allergie
Quand on analyse l'histoire des sciences et de la medecine, jl est tres difficile d'interpreter les ecrits anterieurs a l'imprimerie, surtout quand les neologismes utilises ont ete crees au debut du…
Histamine and Leukotriene Receptor Antagonism in the Treatment of Allergic Rhinitis
Results from meta-analyses indicate that H1 antihistamines and leukotriene antagonists are equally effective in improving symptoms of allergic rhinitis and quality of life, but that both drugs are less effective than intranasal corticosteroids.
Role of histamine H4 receptors in the gastrointestinal tract.
- Medicine, BiologyFrontiers in bioscience
Functional studies with selective H4R ligands demonstrated protective effects in several experimental models of gastric mucosal damage and intestinal inflammation, suggesting a potential therapeutic role of drugs targeting this new receptor subtype in GI disorders, such as allergic enteropathy, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and cancer.
Histamine regulation of innate and adaptive immunity.
- BiologyFrontiers in bioscience
This review discusses histamine receptor expression and differential activation of cells within both the innate and adaptive immune response and the signal transduction mechanisms which influence their activity.
Cardiovascular effects of histamine in three widely diverse species of reptiles
- Biology, MedicineJournal of Comparative Physiology B
In all three species, histamine-induced tachycardia by direct stimulation of histaminergic receptors as well as an indirect activation of adrenoreceptors is found, highlighting a more complex mechanism underlying the action of histamine than previously recognized in reptiles.
Breast reconstruction – current practice and future directions
The potential applications of MSQD conjugated to three novel molecules as theostic tools for both diagnosis and treatment of triple negative breast cancer are demonstrated.
BLOODELECTROLYTESTUDIES DURINGHISTAMINE SHOCKIN DOGS
The observations here presented were made immediately before and during histamine shock in dogs and include serum electrolyte partitions, hematocrit determinations and in certain instances 02 capacity and serum pH.
The response of mast cells and serglycin-dependent proteases to parasitic infection
- Biology, Medicine
MCs are actively involved in the host response to Toxoplasma gondii infection in mice and Dictyocaulus viviparus infection in calves and tryptase positive MCs in the bovine lung and BALF were shown to correlate with disease progression.