The physics, biophysics and technology of photodynamic therapy

@article{Wilson2008ThePB,
  title={The physics, biophysics and technology of photodynamic therapy},
  author={Brian C. Wilson and Michael S. Patterson},
  journal={Physics in Medicine \& Biology},
  year={2008},
  volume={53},
  pages={R61 - R109}
}
Photodynamic therapy (PDT) uses light-activated drugs to treat diseases ranging from cancer to age-related macular degeneration and antibiotic-resistant infections. This paper reviews the current status of PDT with an emphasis on the contributions of physics, biophysics and technology, and the challenges remaining in the optimization and adoption of this treatment modality. A theme of the review is the complexity of PDT dosimetry due to the dynamic nature of the three essential components—light… 

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  • 2015
TLDR
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...

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This paper will attempt to deal with the complex subject of PDT tumor destruction by giving a sequential account of the effects occurring during PDT tissue treatment on a cellular and tissue level.
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