The physician’s role in the protection of human research subjects

@article{Williams2006ThePR,
  title={The physician’s role in the protection of human research subjects},
  author={John R. Williams},
  journal={Science and Engineering Ethics},
  year={2006},
  volume={12},
  pages={5-12}
}
Responsibility for the protection of human research subjects is shared by investigators, research ethics committees, sponsors/funders, research institutions, governments and, the focus of this article, physicians who enrol patients in clinical trials. The article describes the general principles of the patient-physician relationship that should regulate the participation of physicians in clinical trials and proposes guidelines for determining when and how such participation should proceed. The… Expand
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References

SHOWING 1-6 OF 6 REFERENCES
The Nazi Doctors and the Nuremberg Code Human Rights in Human Experimentation
The atrocities committed by Nazi physicians and researchers during World War II prompted the development of the Nuremberg Code to define the ethics of modern medical experimentation utilizing humanExpand
An Ambulance of the Wrong Colour Health Professionals, Human Rights and Ethics in South Africa
Notes on terminology confronting the past health and the apartheid state civilian health services health care in custody health professionals in the South African military the "scientific"Expand
Protecting research subjects--the crisis at Johns Hopkins.
In June 2001, Ellen Roche, a healthy young technician at the Johns Hopkins Asthma and Allergy Center, died during an asthma study. The tragedy prompted several intensive investigations of research ...
Dr. Roger Poisson: "I have learned my lesson the hard way".
  • F. Lowry
  • Computer Science, Medicine
  • CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
  • 1994
Ethics and clinical research.
  • H. Beecher
  • Medicine
  • The New England journal of medicine
  • 1966
Oath of Hippocrates