The physical map of the human RET proto-oncogene.

@article{Pasini1995ThePM,
  title={The physical map of the human RET proto-oncogene.},
  author={Barbara Pasini and Robert M. W. Hofstra and Luo Yin and Renata Bocciardi and Giuseppe Santamaria and P. M. Grootscholten and Isabella Ceccherini and Giovanna Patrone and Manuela Priolo and C. H. Buys},
  journal={Oncogene},
  year={1995},
  volume={11 9},
  pages={1737-43}
}
The RET proto-oncogene, a transmembrane tyrosine kinase receptor, is involved in the development of at least five different disease phenotypes. RET is activated through somatic rearrangements in a number of cases of papillary thyroid carcinoma while germ-line point mutations are associated with three inherited cancer syndromes MEN 2A, MEN 2B and FMTC. Moreover, point mutations or heterozygous deletions of RET are found in the dominant form of Hirschsprung disease or congenital colonic… CONTINUE READING

Connections & Topics

Mentioned Connections BETA
Moreover , point mutations or heterozygous deletions of RET are found in the dominant form of Hirschsprung disease or congenital colonic aganglionosis .
Moreover , point mutations or heterozygous deletions of RET are found in the dominant form of Hirschsprung disease or congenital colonic aganglionosis .
Moreover , point mutations or heterozygous deletions of RET are found in the dominant form of Hirschsprung disease or congenital colonic aganglionosis .
Moreover , point mutations or heterozygous deletions of RET are found in the dominant form of Hirschsprung disease or congenital colonic aganglionosis .
Moreover , point mutations or heterozygous deletions of RET are found in the dominant form of Hirschsprung disease or congenital colonic aganglionosis .
RET is activated through somatic rearrangements in a number of cases of papillary thyroid carcinoma while germ - line point mutations are associated with three inherited cancer syndromes MEN 2A , MEN 2B and FMTC .
RET is activated through somatic rearrangements in a number of cases of papillary thyroid carcinoma while germ - line point mutations are associated with three inherited cancer syndromes MEN 2A , MEN 2B and FMTC .
RET is activated through somatic rearrangements in a number of cases of papillary thyroid carcinoma while germ - line point mutations are associated with three inherited cancer syndromes MEN 2A , MEN 2B and FMTC .
RET is activated through somatic rearrangements in a number of cases of papillary thyroid carcinoma while germ - line point mutations are associated with three inherited cancer syndromes MEN 2A , MEN 2B and FMTC .
RET is activated through somatic rearrangements in a number of cases of papillary thyroid carcinoma while germ - line point mutations are associated with three inherited cancer syndromes MEN 2A , MEN 2B and FMTC .
Moreover , point mutations or heterozygous deletions of RET are found in the dominant form of Hirschsprung disease or congenital colonic aganglionosis .
RET is activated through somatic rearrangements in a number of cases of papillary thyroid carcinoma while germ - line point mutations are associated with three inherited cancer syndromes MEN 2A , MEN 2B and FMTC .
RET is activated through somatic rearrangements in a number of cases of papillary thyroid carcinoma while germ - line point mutations are associated with three inherited cancer syndromes MEN 2A , MEN 2B and FMTC .
All Topics