The photochemistry of 8-bromo-2'-deoxyadenosine. A direct entry to cyclopurine lesions.

Abstract

The UV photolysis of 8-bromo-2'-deoxyadenosine has been investigated in different solvents and in the presence of additives like halide anions. Photolytic cleavage of the C-Br bond leads to formation of the C8 radical. In methanol, subsequent hydrogen abstraction from the solvent is the main radical reaction; however, in water or acetonitrile intramolecular… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.