The photochemical oxidation of A2E results in the formation of a 5,8,5',8'-bis-furanoid oxide.

@article{Dillon2004ThePO,
  title={The photochemical oxidation of A2E results in the formation of a 5,8,5',8'-bis-furanoid oxide.},
  author={James W. Dillon and Zhongli Wang and Luc{\'i}a B Avalle and Elizabeth R Gaillard},
  journal={Experimental eye research},
  year={2004},
  volume={79 4},
  pages={537-42}
}
With age and certain diseases, the retinal pigment epithelium (RPE) accumulates a complex mixture of fluorophores generally called lipofuscin. This mixture has been implicated in those diseases via several possible mechanisms including photochemically mediated damage and detergent effects. Recently, a component of that mixture has been identified, a bis-retinoid pyridinium compound called A2E. Furthermore, the photolysis of this compound has been shown to lead to a series of photooxidation… CONTINUE READING

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