The photochemical binding of bithionol to soluble proteins and peptides.

@article{Delahanty1989ThePB,
  title={The photochemical binding of bithionol to soluble proteins and peptides.},
  author={Jonathan N. Delahanty and J. Catherine Evans and Christopher C. Rowlands and Ruth U Pendlington and M. D. Barratt},
  journal={Biochemical pharmacology},
  year={1989},
  volume={38 21},
  pages={
          3879-83
        }
}

Photochemical binding of photoallergens to human serum albumin: A simple in vitro method for screening potential photoallergens.

Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity.

It is clarified that phosphorylated histone H2AX (γ-H2AX), which was produced with the induction of DNA double-strand breaks, is a sensitive photogenotoxic marker.

Evaluation of chemical phototoxicity, focusing on phosphorylated histone H2AX

It is found that the γ-H2AX assay exhibited high sensitivity and a low false-positive rate as a detection system of genotoxic potential as well as the toxic impact of various environmental stresses such as chemicals, light and/or their coexposure using γ, H2AX.

False-negative chemicals in ESR-based photosafety test (ESR-PT) and their significance for photosafety evaluations: examples of bithionol, fenticlor and cilnidipine.

The electron spin resonance (ESR)-based photosafety test (ESR-PT) is a non-animal prediction test for photosafety evaluations that can be used even for hydrophobic chemicals; the method is based on

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