The photochemical binding of bithionol to soluble proteins and peptides.

@article{Delahanty1989ThePB,
  title={The photochemical binding of bithionol to soluble proteins and peptides.},
  author={J. N. Delahanty and J. Evans and C. Rowlands and R. Pendlington and M. Barratt},
  journal={Biochemical pharmacology},
  year={1989},
  volume={38 21},
  pages={
          3879-83
        }
}
The photochemical reactions of the bacteriocide bithionol (a known photoallergen in man) with soluble proteins and peptides, were investigated. Solutions of human serum albumin (HSA), human gamma-globulin, bovine insulin and poly-L-lysine were irradiated with ultraviolet light of wavelength 313 nm in the presence of [35S]-bithionol and the extent of photochemical (covalent) binding determined. HSA bound at least four molecules of bithionol per molecule of HSA. Bithionol was also found to bind… Expand
Photochemical binding of photoallergens to human serum albumin: A simple in vitro method for screening potential photoallergens.
  • R. Pendlington, M. Barratt
  • Chemistry, Medicine
  • Toxicology in vitro : an international journal published in association with BIBRA
  • 1990
Phosphorylation of histone H2AX is a powerful tool for detecting chemical photogenotoxicity.
Evaluation of chemical phototoxicity, focusing on phosphorylated histone H2AX

References

SHOWING 1-10 OF 17 REFERENCES
Photochemical reactions of fentichlor with soluble proteins.
EVIDENCE FOR A MAJOR STRONG BINDING SITE FOR TETRACHLOROSALICYLANILIDE ON HUMAN SERUM ALBUMIN
Induction of photoallergy in guinea-pigs by injection of photoallergen-protein conjugates.
Photoreactions of 3,3',4',5-tetrachlorosalicylanilide with proteins.
Structure of N-terminal cyanogen bromide fragment of human plasma albumin.
Primary structure of peptides released during activation of human plasminogen by urokinase.
  • B. Wiman
  • Chemistry, Medicine
  • European journal of biochemistry
  • 1973
Photoallergies to fenticlor and Multifungin.
  • J. Burry
  • Medicine
  • Archives of dermatology
  • 1967
...
1
2
...