The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death

@inproceedings{Cameron2014ThePO,
  title={The phosphorylation of Hsp20 enhances its association with amyloid-β to increase protection against neuronal cell death},
  author={Ryan Cameron and Steven D Quinn and Lynn S. Cairns and R W Macleod and Ifor D. W. Samuel and Brian O Smith and J Carlos Penedo and George S Baillie},
  booktitle={Molecular and Cellular Neuroscience},
  year={2014}
}
Up-regulation of Hsp20 protein levels in response to amyloid fibril formation is considered a key protective response against the onset of Alzheimer's disease (AD). Indeed, the physical interaction between Hsp20 and Aβ is known to prevent Aβ oligomerisation and protects neuronal cells from Aβ mediated toxicity, however, details of the molecular mechanism… CONTINUE READING