The phosphonopyruvate decarboxylase from Bacteroides fragilis.

@article{Zhang2003ThePD,
  title={The phosphonopyruvate decarboxylase from Bacteroides fragilis.},
  author={Guofeng Zhang and Jiaying Dai and Zhibing Lu and Debra Dunaway-Mariano},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 42},
  pages={41302-8}
}
The Bacteroides fragilis capsular polysaccharide complex is the major virulence factor for abscess formation in human hosts. Polysaccharide B of this complex contains a 2-aminoethylphosphonate functional group. This functional group is synthesized in three steps, one of which is catalyzed by phosphonopyruvate decarboxylase. In this paper, we report the cloning and overexpression of the B. fragilis phosphonopyruvate decarboxylase gene (aepY), purification of the phosphonopyruvate decarboxylase… CONTINUE READING

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Investigations of 2-Aminoethylphosphonate Biosynthetic Enzymes in Tetrahymena Pyriformis

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