The phosphatidylinositol 3-kinase/akt signaling pathway in medullary thyroid cancer.

@article{Pitt2008TheP3,
  title={The phosphatidylinositol 3-kinase/akt signaling pathway in medullary thyroid cancer.},
  author={Susan C Pitt and Herbert C Chen},
  journal={Surgery},
  year={2008},
  volume={144 5},
  pages={721-4}
}
THYROID CANCER were diagnosed in 2007 according to the American Cancer Society. Medullary thyroid cancer (MTC) accounts for approximately 5% of these carcinomas and arises from calcitonin-secreting parafollicular C cells. While up to 25% of MTCs are hereditary, the majority of cases are sporadic. Hereditary forms of MTC include both multiple endocrine neoplasia 2 types (MEN 2A and MEN 2B) and familial MTC. Mutations of the Rearranged During Transfection (RET) protooncogene on chromosome 10q11… CONTINUE READING

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Antiproliferative effects of Src inhibition on medullary thyroid cancer.

The Journal of clinical endocrinology and metabolism • 2004

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