The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa

@article{Dietrich2006ThePP,
  title={The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa},
  author={Lars E. P. Dietrich and Alexa Price-Whelan and Ashley Petersen and M. Whiteley and Dianne K. Newman},
  journal={Molecular Microbiology},
  year={2006},
  volume={61}
}
Certain members of the fluorescent pseudomonads produce and secrete phenazines. These heterocyclic, redox‐active compounds are toxic to competing organisms, and the cause of these antibiotic effects has been the focus of intense research efforts. It is largely unknown, however, how pseudomonads themselves respond to – and survive in the presence of – these compounds. Using Pseudomonas aeruginosa DNA microarrays and quantitative RT‐PCR, we demonstrate that the phenazine pyocyanin elicits the… 
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