The pharmacotherapy of obsessive-compulsive disorder.

@article{Mcdougle1992ThePO,
  title={The pharmacotherapy of obsessive-compulsive disorder.},
  author={Christopher J. Mcdougle and Wayne K. Goodman and Lawrence H Price},
  journal={Pharmacopsychiatry},
  year={1992},
  volume={26 Suppl 1},
  pages={
          24-9
        }
}
Potent inhibitors of 5-hydroxytryptamine (5-HT) reuptake have clearly been established as the first-line pharmacotherapy for treatment of obsessive-compulsive disorder (OCD). Although a variety of tricyclic antidepressants and monoamine oxidase inhibitors have similar efficacy in the treatment of depression and panic disorder, potent blockade of 5-HT transport appears to be a prerequisite for effective treatment of OCD. Adding agents that enhance 5-HT neurotransmission to ongoing treatment in… CONTINUE READING

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